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›› 2013, Vol. 33 ›› Issue (1): 113-116.doi: 10.3969/j.issn.0253-2417.2013.01.021

• 1研究报告 • Previous Articles     Next Articles

Chemical Components of Chinese Herbal Formula of Gankang

ZHANG Jin-cai, CHEN Guang-ying, HAN Chang-ri, CHEN Wen-hao, ZHAN Xue-mei, ZHANG Wei   

  1. Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China
  • Received:2012-02-28 Revised:1900-01-01 Online:2013-02-28 Published:2013-02-28

Abstract: To study the hypoglycemic mechanism from Chinese Herbal Formula of Gankang, the chemical constituents of its active fraction were investigated in this study. Thirteen compounds were isolated and purified by silica gel column, Sephadex LH-20, and C18 chromatography, respectively. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data. Thirteen compounds were identified as: (Z)-resveratrol(3,5,4'-trihydroxystilbene)-3-O-β-glucoside(1), kaemperol-3-O-β-D-glucopyranoside(2), kaemperol(3), 4'-dihydrophaseic acid(4), leptosphaepin(5), arbutin(6), 4-caffeoyl quinic acid(7), 3,4-dimethoxyphenyl-ethyl-ether(8), 2-butylated-4-hydroxyanisole(9), α-tocoquinone(10), isovanillic acid(11), mannitol(12) and β-daucosterol(13). They are all firstly isolated from this traditional Chinese medicine

Key words: traditional chinese material compound, chemical components, 4'-dihydrophaseic acid, leptosphaepin

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