[1] CHIHARA G, MAEDA Y, HAMURO J, et al.Inhibition of mouse Sarcoma 180 by polysaccharides from Lentinus edodes (Berk)Sing[J].Nature, 1969, 222(5194):687-688. [2] IZYDORCZYK M.Understanding the Chemistry of Food Carbohydrate[M]//CUI S W.Food carbohydrates:Chemistry, physical properties, and applications.New York:CRC Press, 2005:1-66. [3] ISRAILIDES C, KLETSAS D, ARAPOGLOU D, et al.In vitro cytostatic and immunomodulatory properties of the medicinal mushroom Lentinula edodes[J].Phytomedicine, 2008, 15(7):512-519. [4] LEE J S, HONG E K.Immunostimulating activity of the polysaccharides isolated from Cordyceps militaris[J].International Immunopharmacology, 2011, 11(9):1226-1233. [5] PARK S E, YOO H S, JIN C Y, et al.Induction of apoptosis and inhibition of telomerase activity in human lung carcinoma cells by the water extract of Cordyceps militaris[J].Food and Chemical Toxicology, 2009, 47(7):1667-1675. [6] BAE J S, JANG K H, YIM H, et al.Polysaccharides isolated from Phellinus gilvus inhibit melanoma growth in mice[J].Cancer Letters, 2005, 218(1):43-52. [7] SHAMTSYAN M, KONUSOVA V, MAKSIMOVA Y, et al.Immunomodulating and anti-tumor action of extracts of several mushrooms[J].Journal of Biotechnology, 2004, 113(1):77-83. [8] ZHAO Li-yan, DONG Yan-hong, CHEN Gui-tang, et al.Extraction, purification, characterization and antitumor activity of polysaccharides from Ganoderma lucidum[J].Carbohydrate Polymers, 2010, 80(3):783-789. [9] CAO Qi-zhen, LIN Zhi-bin.Ganoderma lucidum polysaccharides peptide inhibits the growth of vascular endothelial cell and the induction of VEGF in human lung cancer cell[J].Life Sciences, 2006, 78(13):1457-1463. [10] STANLEY G, HARVEY K, SLIVOVA V, et al.Ganoderma lucidum suppresses angiogenesis through the inhibition of secretion of VEGF and TGF-β1 from prostate cancer cells[J].Biochemical and Biophysical Research Communications, 2005, 330(1):46-52. [11] CHEN Xiao-ping, CHEN Yuan, LI Shui-bing, et al.Free radical scavenging of Ganoderma lucidum polysaccharides and its effect on antioxidant enzymes and immunity activities in cervical carcinoma rats[J].Carbohydrate Polymers, 2009, 77(2):389-393. [12] ZHANG Mei, ZHU Lin, CUI S W, et al.Fractionation, partial characterization and bioactivity of water-soluble polysaccharides and polysaccharide-protein complexes from Pleurotus geesteranus[J].International Journal of Biological Macromolecules, 2011, 48(1):5-12. [13] VAZ J A, HELENO S A, MARTINS A, et al.Wild mushrooms Clitocybe alexandri and Lepista inversa:In vitro antioxidant activity and growth inhibition of human tumour cell lines[J].Food and Chemical Toxicology, 2010, 48(10):2881-2884. [14] YAMAMOTO K, KIMURA T, SUGITACHI A, et al.Anti-angiogenic and anti-metastatic effects of β-1, 3-D-glucan purified from hanabiratake, sparassis crispa[J].Biological & Pharmaceutical Bulletin, 2009, 32(2):259-263. [15] YU Ching-han, KAN Shu-fen, SHU Chin-hang, et al.Inhibitory mechanisms of agaricus blazei murill on the growth of prostate cancer in vitro and in vivo[J].Journal of Nutritional Biochemistry, 2009, 20(10):753-764. [16] FULLERTON S A, SAMADI A A, TORTORELIS D G, et al.Induction of apoptosis in human prostatic cancer cells with β-glucan(Maitake Mushroom polysaccharide)[J].Molecular Urology, 2000, 4(1):7-13. [17] SLATON J, VERNERIS M, LU H, et al.East meets west:The mushroom extract PSK enhances docetaxel therapy for castrate resistant prostate cancer[J].Journal of Urology, 2011, 185(4):e295. [18] CAO Wei, LI Xiao-qing, WANG Xiang, et al.A novel polysaccharide, isolated from Angelica sinensis (Oliv.) Diels induces the apoptosis of cervical cancer HeLa cells through an intrinsic apoptotic pathway[J].Phytomedicine, 2010, 17(8):598-605. [19] HAN S B, LEE C W, KANG J S, et al.Acidic polysaccharide from Phellinus linteus inhibits melanoma cell metastasis by blocking cell adhesion and invasion[J].International Immunopharmacology, 2006, 6(4):697-702. [20] KIM G Y, CHOI G S, LEE S H, et al.Acidic polysaccharide isolated from Phellinus linteus enhances through the up-regulation of nitric oxide and tumor necrosis factor-α from peritoneal macrophages[J].Journal of Ethnopharmacology, 2004, 95(1):69-76. [21] ZHANG Mei, CHEUNG P C K, CHIU L C M, et al.Cell-cycle arrest and apoptosis induction in human breast carcinoma MCF-7 cells by carboxymethylated β-glucan from the mushroom sclerotia of Pleurotus tuber-regium[J].Carbohydrate Polymers, 2006, 66(4):455-462. [22] RAJARATHNAM S, SASHIREKHA M N.Encyclopedia of Food Science, Food Technology and Nutrition[M].London:Elsevier Science Ltd., 2003:4048-4054. [23] AOUADI S, HEYRAUD A, SEIGLE-MURANDI F, et al.Structure and properties of an extracellular polysaccharide from Laetisaria arvalis, evaluation of its antitumour activity[J].Carbohydrate Polymers, 1991, 16(2):155-165. [24] ZHANG Mei, CHEUNG P C K, ZHANG L, et al.Carboxymethylated β-glucans from mushroom sclerotium of Pleurotus tuber-regium as novel water-soluble anti-tumor agent[J].Carbohydrate Polymers, 2004, 57(3):319-325. [25] ZHANG G, SUN J, WANG H, et al.First isolation and characterization of a novel lectin with potent antitumor activity from a Russula mushroom[J].Phytomedicine, 2010, 17(10):775-781. [26] 吕国英, 范雷法, 张作法, 等.香菇多糖研究进展[J].浙江农业学报, 2009, 21(2):183-188. [27] 王振河, 霍云凤.裂褶菌及裂褶菌多糖研究进展[J].微生物学杂志, 2006, 26(1):73-76. [28] 王菲菲, 郝利民, 贾士儒, 等.云芝多糖研究进展[J].食品与发酵工业, 2012, 38(6):148-152. [29] LIU F, OOI V E C, CHANG S T.Anti-tumour components of the culture filtrates from Tricholoma sp[J].World Journal of Microbiology and Biotechnology, 1995, 11(5):486-490. [30] 毛健, 马海乐.灵芝多糖的研究进展[J].食品科学, 2010, 31(1):295-299. [31] 汲晨锋, 岳磊.香菇多糖的化学及抗肿瘤作用研究进展[J].中国药学杂志, 2013, 48(18):1536-1539. [32] ZHANG Li-na, LI Xue-lian, XU Xiao-juan, et al.Correlation between antitumor activity, molecular weight, and conformation of lentinan[J].Carbohydrate Research, 2005, 340(8):1515-1521. [33] MIYAZAKI T, OIKAWA N, YADOMAE T, et al.Relationship between the chemical structure and anti-tumour activity of glucans prepared from Grifora umbellate[J].Carbohydrate Polymers, 1979, 69(1):165-170. [34] 牛爽, 郝利民, 赵树欣, 等.茯苓多糖的研究进展[J].食品科学, 2012, 33(13):348-353. [35] YADOMAE T.Structure and biological activities of fungal β-1, 3-glucans[J].Yakugaku Zasshi, 2000, 120(5):413-431. [36] ASIF A, FAQIR M A, TAHIR Z, et al.Beta glucan:A valuable functional ingredient in foods[J].Critical Reviews in Food Science and Nutrition, 2012, 52(3):201-212. [37] USUI S, TOMONO Y, SAKAI M, et al.Preparation and antitumor activities of β-(1→6) branched (1→3)-β-D-glucan derivatives[J].Biological & Pharmaceutical Bulletin, 1995, 18(12):1630-1636. [38] ZAIDMAN B Z, YASSIN M, MAHAJNA J, et al.Medicinal mushroom modulators of molecular targets as cancer therapeutics[J].Applied Microbiology and Biotechnology, 2005, 67(4):453-468. [39] IKEKAWA T.Beneficial effects of edible and medicinal mushrooms on health care[J].International Journal of Medicinal Mushrooms, 2001, 3(4):291-298. [40] HASHIMOTO T, NONAKA Y, MINATO K, et al.Suppressive effect of polysaccharides from the edible and medicinal mushrooms, Lentinus edodes and Agaricus blazei on the expression of cytochrome P450s in mice[J].Bioscience Biotechnology and Biochemistry, 2002, 66(7):1610-1614. [41] OKAMOTO T, KODOI R, NONAKA Y, et al.Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver[J].Biofactors, 2004, 21(1/2/3/4):407-409. [42] SREENIVASULU K, VIJAYALAKSHMI M, SAMBASIVARAO K.hTERT gene inhibition studies in cancer cells by using polysaccharide lentinan[J].Journal of Medical Genetics and Genomics, 2011, 3(1):7-12. [43] LIMA P L, DELMANTO R D, SUGUI M M, et al.Letinula edodes (Berk)Pegler (Shiitake)modulates genotoxic and mutagenic effects induced by alkylating agents in vivo[J].Mutation Research, 2001, 496(1/2):23-32. [44] ZHANG Yang-yang, LI Sheng, WANG Xiao-hua, et al.Advances in lentinan:Isolation, structure, chain conformation and bioactivities[J].Food Hydrocolloid, 2011, 25(2):196-206. [45] ADACHI Y, OKAZAKI M, OHNO N, et al.Enhancement of cytokine production by macrophages stimulated with (1→3)-β-D-glucan, Grifolan (GRN), isolated from Grifola frondosa[J].Biological & Pharmaceutical Bulletin, 1994, 17(12):1554-1560. [46] CHEN Yue-ya, CHANG Hung-min.Antiproliferative and differentiating effects of polysaccharide fraction from fu-ling (Poria cocos) on human leukemic U937 and HL-60 cells[J].Food and Chemical Toxicology, 2004, 42(5):759-769. [47] SIA G M, CANDLISH J K.Effects of Shiitake (Lentinus edodes) extract on human neutrophils and the U937 monocytic cell line[J].Phytotherapy Research, 1999, 13(2):133-137. [48] CHOW L W, LO C S, LOO W T, et al.Polysaccharide peptide mediates apoptosis by up-regulating p21 gene and down-regulating Cyclin D1 gene[J].American Journal of Chinese Medicine, 2003, 31(1):1-9. [49] RUAN Zheng, SU Jie, DAI Han-chuan, et al.Characterization and immunomodulating activities of polysaccharide from Lentinus edodes[J].International Immunopharmacology, 2005, 5(5):811-820. [50] HSIEH T C, KUNICKI J, DARZYNKIEWICZ Z, et al.Effects of extracts of Coriolus versicolor on cell-cycle progression and expression of interleukins-1β, -6, and -8 in promyelocytic HL-60 leukemic cells and mitogenically stimulated and nonstimulated human lymphocytes[J].The Journal of Alternative and Complementary Medicine, 2002, 8(5):591-602. [51] GUO C X, WONG K H, CHEUNG P C K, et al.Hot Water extract of the sclerotium of Polyporus rhinocerus Cooke enhances the immune functions of murine macrophages[J].International Journal of Medicinal Mushrooms, 2011, 13(3):237-244. [52] 欧阳天贽, 李小定, 荣建华.真菌多糖抗肿瘤及免疫调节作用研究进展[J].天然产物研究与开发, 2006, 18(3):524-528. [53] BROWN G D, GORDON S.Immune recognition of fungal β-glucans[J].Cellular Microbiology, 2005, 7(4):471-479. |