异长叶烯酮的绿色合成研究

doi:10.3969/j.issn.0253-2417.2015.03.017

Abstract

Abstract: Isolongifolenone was synthesized by using heavy turpentine as the starting material.Firstly,the heavy turpentine was converted to isolongifolene by isomerization reaction with BF₃ (C₂H₅)₂O as catalyst.Isolongifolenone was finally obtained from isolongifolene by allylic oxidation with tert-butyl hydroperoxide (TBHP) as oxidizer,Cu as catalyst and tert-butyl alcohol (TBA) as solvent.By investigating the influence of different react conditions on the oxidation of isolongifolene,the optimum conditions were determined as follows:the mass fraction of Cu 3% (based on the mass of isolongifolene),the mole ratio of TBHP and isolongifolene 3.5:1,the mass ratio of TBA and isolongifolene 1:1,reaction temperature 80 ℃ and reaction time 12 h.The yield of isofolenone was over 93%,and the purity was 98.75% under these conditions.

Key words: heavy turpentine, isolongifolene, allylic oxidation, isolongifolenone

CLC Number:

TQ35

PENG Han, YANG Li-juan, XU Xu, WANG Shi-fa. Green Synthesis of Isolongifolenone[J]. Chemistry and Industry of Forest Products, 2015, 35(3): 97-103.

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Green Synthesis of Isolongifolenone

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