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Chemistry and Industry of Forest Products ›› 2015, Vol. 35 ›› Issue (6): 148-152.doi: 10.3969/j.issn.0253-2417.2015.06.024

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Research Progress on Preparation Methods and Applications of Dextran-based Hydrogels

LIN Yan, FANG Gui-gan, HUO Dan   

  1. Institute of Chemical Industry of Forest Products, CAF;National Engineering Lab.for Biomass Chemical Utilization; Key and Open Lab.of Forest Chemical Engineering, SFA.Key Lab.of Biomass Energy and Material, Jiangsu Province, Nanjing 210042, China
  • Received:2014-07-08 Online:2015-12-25 Published:2015-12-28

Abstract: As a kind of biological polysaccharide, dextran contains many free hydroxyl groups on the main chain, which is convenient for modification and crosslinking.The hydrogels prepared by dextran exhibited excellent swelling property, biocompatibility and biodegradability.Dextran is widely applied in the fields of substance separation, drug delivery and tissue engineering.Kinds of common preparation methods of dextran-based hydrogels, including repeated freezing-thawing method, chemical crosslinking method, grafting modification method, and free radical polymerization, have been summarized, Besides, the applications of dextran-based hydrogels in recent years are reviewed and the future developments are discussed in present study.

Key words: dextran, hydrogel, separation, tissue engineering, drug releasing

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