3'-(3,3-二甲基双环[2.2.1]庚-2-亚基)-5'-苯基-异噁唑啉的合成与表征

doi:10.3969/j.issn.0253-2417.2018.06.015

Abstract

Abstract: The unreported 3'-(3,3-dimethylbicyclo[2.2.1] hept-2-ylidene)-5'-phenyl-isoxazoline was synthesized by cycloaddition reaction of 2-(3,3-dimethylbicyclo[2.2.1] heptan-2-ylidene)acetaldehyde oxime (camphene aldoxime, CAO) and syrene. The structure of the product was identified by FT-IR, GC-MS, ¹H NMR and ¹³C NMR. The effects of the types of solvent, type and dosage of catalyst, amount of oxidant Oxone, dosage of syrene and reaction time on reaction rate and product yield were discussed. The optimum conditions were obtained as follows:potassium chloride as the catalyst, 50% methanol as solvent, n(camphene aldoxime):n(potassium chloride):n(Oxone):n(syrene)=1.0:0.5:1.5:2.0, reaction time 10 h. Under the above conditions, the product yield was 88.07%.

Key words: camphene aldoxime, cycloaddition reaction, isoxazoline compound, structure characterization

CLC Number:

TQ35

HUANG Jing, BAO Han, ZHANG Xia, MO Yue, LUO Jinyue, LIU Zuguang. Synthesis and Characterization of 3'-(3,3-Dimethylbicyclo[2.2.1] hept-2-ylidene)-5'-phenyl-isoxazoline[J]. Chemistry and Industry of Forest Products, 2018, 38(6): 110-116.

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Synthesis and Characterization of 3'-(3,3-Dimethylbicyclo[2.2.1] hept-2-ylidene)-5'-phenyl-isoxazoline

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