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Chemistry and Industry of Forest Products ›› 2019, Vol. 39 ›› Issue (6): 1-12.doi: 10.3969/j.issn.0253-2417.2019.06.001

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Research Progress in Application of Ionic Liquid in Extraction and Separation of Natural Products

Leilei LIU(),Yicong WANG   

  1. Key Laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Zhangjiajie 427000, China
  • Received:2019-05-06 Online:2019-12-28 Published:2019-12-21
  • Supported by:
    国家自然科学基金资助项目(21864012);林产化工实验室开放课题资助项目(JDZ201801);杜仲综合利用实验室开放课题资助项目(DZL201801)

Abstract:

Ionic liquid is a low-temperature molten salt composed of anion and cation. It has almost no vapor pressure, good chemical stability, strong solubility, designable structure and outstanding advantages. It is considered as a new type of "green solvent" that can replace traditional solvent. Ionic liquid has been extensively applied in the separation and purification of natural products. In this paper, the application progress of ionic liquids in the separation of flavonoids, terpenes, alkaloids, pigments and other natural products were reviewed from the aspects of ionic liquids combined with ultrasonic and microwave technology, aqueous two-phase extraction, enzymatic assisted and solid-phase extraction in recent years. The properties and separation mechanism of ionic liquids combined with other technologies were introduced. The problems such as high viscosity, difficult recovery and serious loss, would be discussed, and the corresponding solutions would be put forward to provide reference for the application of ionic liquids in the separation of natural components.

Key words: ionic liquids, natural products, ultrasonic-assisted extraction, microwave-assisted extraction, ionic liquids aqueous two-phase extraction

CLC Number: