靶向分子印迹吸附材料分离林源活性成分的研究进展

doi:10.3969/j.issn.0253-2417.2022.04.016

Abstract

Abstract:

China was rich in forest resources, and it was an important direction and approach of the development of forestry industry for exploiting the active components of forest resources which were beneficial to human health. With the rapid development of forestry bio-agent industry based on the active components as important material basis in China, targeted molecular imprinting materials have important industrial application value in the accurate separation and high-value processing of forest active components. This article introduced the principle and classification of targeted molecular imprinting technology, as well as the carrier types of several new-style targeted molecularly imprinted adsorption materials in recent years, mainly include graphene, silica, carbon dots and bio-based carriers. It focused on the application status in the separation of flavonoids, polyphenols, alkaloids, organic acids and other forest source active ingredients by targeted molecularly imprinted adsorption materials. Finally, the development of targeted molecular imprinting materials for the separation of active components from forest sources was summarized and prospected, the limitation of targeted molecular imprinting materials and the development trend of targeted molecular imprinting materials in the separation of active components from forest sources were also analyzed.

Key words: targeted molecular imprinting materials, active components from forest sources, specific separation, carrier

CLC Number:

TQ35
TQ9

Mujie LYU, Litao WANG, Jiandong WANG, Jinsong CAO, Haojie JIN, Yujie FU. Research Progress on Separation of Active Components from Forest Sources by Targeted Molecular Imprinting Materials[J]. Chemistry and Industry of Forest Products, 2022, 42(4): 107-118.

Figures/Tables 6

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Table 1

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聚合方法 aggregation method	优点 advantage	缺点 disadvantage
本体聚合 bulk polymerization	操作容易，设备要求低^[10]the operation is simple and easy, and the requirements for hardware equipment are not high^[10]	需后处理^[11]follow-up processing required ^[11]
沉淀聚合 precipitation polymerization	无需后处理，体系纯，特异性吸附强^[17]no follow-up processing required and the system without surfactants is more pure and has stronger specific adsorption^[17]	溶剂要求高，需求量大^[12]the solvent demand is large, and the solvent used needs to be able to dissolve all the substances participating in the reaction^[12]
乳液聚合 emulsion polymerization	无需后处理，重复利用率高，水溶性高^[18]no follow-up processing required, and the reuse rate is high; and the water-soluble compounds can be separated^[18]	配比复杂，特异性吸附弱^[19]the ratio of organic phase to water phase needs to be adjusted many times; the system has weak specific adsorption^[19]
悬浮聚合 suspension polymerization	无需后处理，材料粒径大小可控^[18]no follow-up processing required, and the particle size is controllable^[18]	制备繁琐，应用局限性大^[20]the preparation process is lengthy; the application is limited due to the influence of the solvent^[20]
原位聚合 in-situ polymerization	更适用于制作分子印迹色谱柱^[21]it is more suitable for making molecularly imprinted chromatographic columns^[21]	特异性吸附弱，重复利用率低^[20]the specific adsorption is not strong, and the reuse rate is low^[20]

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Research Progress on Separation of Active Components from Forest Sources by Targeted Molecular Imprinting Materials

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