Welcome to Chemistry and Industry of Forest Products,

Chemistry and Industry of Forest Products ›› 2014, Vol. 34 ›› Issue (1): 128-134.doi: 10.3969/j.issn.0253-2417.2014.01.022

Previous Articles    

Review on Anti-tumor Polysaccharides in Mushroom

JI Chen-feng1,2, YUE Lei3   

  1. 1. Engineering Research Center of Natural Anticancer Drugs, Ministry of Education, Harbin University of Commerce, Harbin 150076, China;
    2. Center of Research on Life Science and Environmental Science, Harbin University of Commerce, Harbin 150076, China;
    3. Department of Biological Science and Engineering, Harbin Institute of Technology, Harbin 150006, China
  • Received:2013-03-29 Online:2014-02-25 Published:2014-03-05

Abstract: Mushrooms are recognized as functional foods and have credible nutritional and medicinal values. Polysaccharide is one of the most bioactive components in mushrooms and exhibits anti-tumor and immunostimulating activities. Numerous polysaccharides with anti-tumor activity have been extracted from a variety of mushrooms, but there are many differences in their chemical composition, structure and anti-tumor activity. This review aims to integrate the R&D progress of anti-tumor polysaccharides in mushrooms which include mushroom polysaccharides with anti-tumor activity, chemistry of mushroom polysaccharides, relationship between structure and anti-tumor activities of mushroom polysaccharides, anti-tumor activity and mechanisms of mushroom polysaccharides. And this review also looks forward to the future studies on receptors and signal transduction pathway, structure activity relationship and pharmacokinetics of polysaccharides.

Key words: mushroom, anti-tumor, polysaccharide, study

CLC Number: