去氢枞酸衍生物生物活性研究新进展

›› 2012, Vol. 32 ›› Issue (6): 99-106.

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Recent Advances on Biologic Activity of Dehydroabietic Acid Derivatives

CUI Yan-jie¹, RAO Xiao-ping¹, SHANG Shi-bin¹, SONG Jie²

1. Institute of Chemical Industry of Forest Products,CAF;National Engineering Lab.for Biomass Chemical Utilization; Key and Open Lab.of Forest Chemical Engineering,SFA;Key Lab.of Biomass Energy and Material, Jiangsu Province, Nanjing 210042, China;2. Department of Chemistry and Biochemistry, University of Michigan-Flint, Flint MI 48502, USA

Received:2011-12-07 Revised:1900-01-01 Online:2013-12-30 Published:2013-12-30

Abstract

Abstract: Dehydroabietic acid is an important derivative of rosin. It has benzene ring and several chiral centers, and its derivatives exhibit wide range of bioactivities. They have important application in the pharmaceutical and insecticide fields. According to the structural characteristics, a series of bioactive derivatives of dehydroabietic acid were synthesized by typical carboxyl reaction, including esterification, synthesizing acyl chloride, being amine or alcohol by reduction, decarboxylated degradation, and electrophilic substitutions, removing isopropyl from aromatic ring. In this paper, recent advances on biologic activity of dehydroabietic acid derivatives are summarized from two aspects,i.e. carboxyl modification and aromatic modification.

Key words: dehydroabietic acid, derivatives, biologic activity

CLC Number:

TQ351.47

CUI Yan-jie;RAO Xiao-ping;SHANG Shi-bin;SONG Jie. Recent Advances on Biologic Activity of Dehydroabietic Acid Derivatives[J]. , 2012, 32(6): 99-106.

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Recent Advances on Biologic Activity of Dehydroabietic Acid Derivatives

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