Abstract: A new method,namely microwave-assisted extraction(MAE),is used to extract baicalin from S. baicalensis.Water,ethanol,chloroform,n-hexane,petroleum were used separately to extract baicalin in a MAE apparatus.The result showed the optimum condition as follows:60% alcohol as sovent,granularity of raw material 200 mesh,duration of microwave irradiation 8 min.Effects of different solvents,different grain sizes of S. baicalensis Georgi and duration of microwave irradiation on yield of baicalin were discussed.Results showed that microwave-assisted extraction is (efficient),simple and rapid for extraction of baicalin from S. baicalensis.

Key words: microwave-assisted extraction, Scutellaria baicalensis Georgi, baicalin