欢迎访问《林产化学与工业》，
林产化学与工业

林产化学与工业 ›› 2009, Vol. 29 ›› Issue (3): 69-72.

• 研究报告 • 上一篇    下一篇

α-蒎烯合成2-羟基-3-蒎酮的研究

臧运晓1,2, 哈成勇1, 沈丹丹1,2, 沈敏敏1   

  1. 1. 中国科学院, 广州化学研究所, 纤维素化学重点实验室, 广东 广州 510650;2. 中国科学院 研究生院, 北京 100039
  • 收稿日期:2008-05-07 修回日期:1900-01-01 出版日期:2009-06-30 发布日期:2009-06-30
  • 通讯作者: 哈成勇,研究员,博士生导师,长期从事天然产物化学理论和应用研究;E-mail:cyha@gic.ac.cn。

Study on Synthesis of 2-Hydroxy-3-Pinanone from α-Pinene

ZANG Yun-xiao1,2, HA Cheng-yong1, SHEN Dan-dan1,2, SHEN Min-min1   

  1. 1. Key Laboratory of Cellulose and Lignocellulosics Chemistry, Chinese Academy of Sciences, Guangzhou 510650, China;2. Graduate School of Chinese Academy of Sciences, Beijing 100039, China
  • Received:2008-05-07 Revised:1900-01-01 Online:2009-06-30 Published:2009-06-30

PDF (PC)

906

摘要： 研究了高锰酸钾氧化α-蒎烯合成2-羟基-3-蒎酮的工艺条件,对助溶剂等影响因素进行了探讨,较优工艺条件为:以叔丁醇为助溶剂,不改变pH值,温度0～5℃,KMnO4与α-蒎烯的物质的量比为1.7:1～1.8:1,先加α-蒎烯后加KMnO4。所得2-羟基-3-蒎酮采用IR、MS、1H NMR、13CNMR 进行了表征,产率达 60%,与文献相同,助溶剂改用叔丁醇后回收率>90%,高于原用助溶剂丙酮(回收率 70%)。

关键词: α-蒎烯, 2-羟基-3-蒎酮

Abstract: The synthetic technology of 2-hydroxy-3-pinanone from α-pinene was studied. Affecting factors such as cosolvent were investigated. The optimum technology was obtained as follows:using tert-butyl alcohol as cosolvent, taking no measure to change pH value, reaction temperature 0-5℃, ratio of n(KMnO4):n(α-pinene) 1.7:1-1.8:1, addition of potassium permanganate after α-pinene. The structure of the product was characterized by IR, MS, 1HNMR and 13CNMR. The yield of 2-hydroxy-3-pinanone was up to 60%, ashigh as the literatures reported before. The recovery of tert-butyl alcohol washigher than 90%, which washigher than that of acetone (70%), the cosolvent used ever before.

Key words: α-pinene, 2-hydroxy-3-pinanone

中图分类号: 

版权所有 © 中国林业科学研究院林产化学工业研究所　苏ICP备08107184号-3