Abstract: Proanthocyanidins were extracted and purified from Rosa laevigata and grape skin. The antioxidant activities of purified proanthocyanidins were investigated by testing scavening effects of ·OH, O₂^-·, NO₂^- and against the peroxidation of oils. The results showed that at the same proanthocyanidin concentration of 0.5 g/L, the scavenging rate to ·OH,O₂^-· and NO₂^- was 98.32%, 95.93%, 96.39% of proanthocyanidins from R. laevigata, and 42.21%, 24.42%, 38.51% of proanthocyanidins from grape skin, respectively. The peroxide value of oil was 0.098 and 0.103 mmol/kg for proanthocyanidins from R. laevigata and grape skin, respectively. The results indicated that purified proanthocyanidins from R. laevigata possessed better antioxidant activity than those from grape skin.