N-氨乙基萜品烯马来酰亚胺基磺酰胺化合物的合成及抑菌活性

doi:10.3969/j.issn.0253-2417.2014.03.013

Abstract

Abstract: α-Pinene (1) was converted into α-terpinene(2) by Wagner-Meerwein rearrangement,followed by Diels-Alder cycloaddtion reaction of 2 with maleic anhydride to obtain α-terpinene-maleic anhydride adduct(3). Then, twelve novel N-aminoethyl-terpinene-maleimide-based sulfamide compounds(5a-5l) were synthesized by the reaction of compound 3 with N-aryl sulfonyl ethylenediamine(4). The target compounds were characterized by means of FT-IR, ¹H NMR, ¹³C NMR, ESI-MS, and elemental analysis. The preliminary bioassay showed that the title compounds exhibited a certain fungicidal activities. Among then, compound 5c(R=3-CH₃) had inhibition rates of 68.8%, 68.3%, 62.3% and 53.8% against Cercospora rachidicola, Alternaria solani, Physalospora piricola and Gibberella zeae at the concentration of 50 mg/L, respectively.

Key words: α-pinene, N-aminoethyl-terpinene-maleimide-based sulfamide, synthesis, fungicidal activities

CLC Number:

TQ351

LIN Zhi-duo, DUAN Wen-gui, LIN Gui-shan, LIAO Jing-ni, LAI Gang, YIN Xian-long, LEI Fu-hou. Syntheses and Fungicidal Activities of N-Aminoethyl-terpinene- maleimide-based Sulfamide Compounds[J]. Chemistry and Industry of Forest Products, 2014, 34(3): 73-81.

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Syntheses and Fungicidal Activities of N-Aminoethyl-terpinene- maleimide-based Sulfamide Compounds

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