N-(5-去氢枞基-1,3,4-噻二唑-2-基-)-N'-取代基硫脲衍生物的合成及杀虫活性的研究

doi:10.3969/j.issn.0253-2417.2015.02.002

Abstract

Abstract: In order to search for biorational pesticides, a series of novel 1,3,4-thiadiazole thiourea derivatives (3a-3k) containing dehydroabietic acid (DHA) structure were designed and synthesized. Their structures were characterized by IR, MS, NMR, and elemental analysis. The insecticidal activities were investigated against cotton bollworm (Helicoverpa armigera), corn borer (Ostrinia nubilalis), and diamondback moth (Plutella xylostella). The preliminary bioassay showed that, at the concentration of 200 mg/L, compounds 3a and 3c exhibited excellent insecticidal activities against H. armigera, with mortality rates of 93.3% and 83.3%, respectively, and compounds 3b, 3c, 3d, and 3i displayed moderate insecticidal activities against O. nubilalis with mortality rates of 66.7%, 66.7%, 73.3%, and 60%, respectively. In addition, the structure-insecticidal activity relationship of these compounds was discussed,too.

Key words: dehydroabietic acid, 1,3,4-thiadiazole, thiourea, synthesis, insecticidal activity

CLC Number:

TQ35

MO Qi-jin MO Qi-jin, LIU Lu-zhi, DUAN Wen-gui, CEN Bo, LIN Gui-shan, CHEN Nai-yuan, HUANG Yan, LIU Bu-ming. Synthesis and Insecticidal Activities of N-(5- Dehydroabietyl-1,3,4-thiadiazol-2-yl)- N'-substituted Thioureas[J]. Chemistry and Industry of Forest Products, 2015, 35(2): 8-16.

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Synthesis and Insecticidal Activities of N-(5- Dehydroabietyl-1,3,4-thiadiazol-2-yl)- N'-substituted Thioureas

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