Abstract: Gastritis models induced by pyloric ligation, ethanol and acetic acid in rats were used to investigate the anti-gastric ulcer action of chlorophyll-carotene paste from pine needles. The gastric ulcer area, gastric juice quantity, pH value, pepsin activity were measured and pathological slices were examined. The results showed that chlorophyll-carotene paste from pine needles groups with different dosages of 0.75, 1.50 and 2.25 g/kg inhibited gastric secretion, increased gastric juice pH value and decreased pepsin activity remarkably(P<0.01), It also greatly inhibited the formation of gastric ulcers induced by pyloric ligation, ethanol and acetic acid(P<0.01). The inhibitory rates at the dosage of 2.25g/kg were 84.39%, 65.33% and 80.68% respectively. It was seen that Chlorophyll-carotene paste from pine needles had preventive and therapeutic effects on experimental gastric ulcer.

Key words: pine needles, chlorophyll-carotene paste, gastirc ulcer