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林产化学与工业 ›› 2015, Vol. 35 ›› Issue (4): 151-158.doi: 10.3969/j.issn.0253-2417.2015.04.024

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迷迭香酸的提取纯化及生物活性研究进展

程贤1, 毕良武1,2, 赵振东1,2, 夏田娟1   

  1. 1. 中国林业科学研究院 林产化学工业研究所;生物质化学利用国家工程实验室;国家林业局 林产化学工程重点开放性实验室;江苏省 生物质能源与材料重点实验室, 江苏 南京 210042;
    2. 中国林业科学研究院 林业新技术研究所, 北京 100091
  • 收稿日期:2014-04-09 出版日期:2015-08-25 发布日期:2015-08-29
  • 通讯作者: 毕良武,研究员,博士,博士生导师,研究领域为天然产物化学与利用;E-mail:biliangwu@126.com。 E-mail:biliangwu@126.com
  • 作者简介:程贤(1990—),女,山东兖州人,硕士生,从事天然产物化学与利用研究;E-mail:gudaoxifeng13@163.com
  • 基金资助:
    引进国际先进林业科学技术项目(2011-4-01)

Research Progress on Extraction, Purification and Biological Activities of Rosmarinic Acid

CHENG Xian1, BI Liang-wu1,2, ZHAO Zhen-dong1,2, XIA Tian-juan1   

  1. 1. Institute of Chemical Industry of Forest Products, CAF;National Engineering Lab.for Biomass Chemical Utilization; Key and Open Lab.of Forest Chemical Engineering, SFA;Key Lab.of Biomass Energy and Material, Jiangsu Province, Nanjing 210042, China;
    2. Research Institute of Forestry New Technology, CAF, Beijing 100091, China
  • Received:2014-04-09 Online:2015-08-25 Published:2015-08-29

摘要: 迷迭香酸作为强抗氧化剂,具有抗菌、抗炎、抗病毒、抗肿瘤等多种生物活性。介绍了迷迭香酸的提取及纯化方法,重点讨论了其在抗菌抗病毒、抗氧化及清除自由基、抗炎及免疫调节、保护神经系统、抗辐射抗肿瘤、抑制黄嘌呤氧化酶和保护肝脏与肺等多方面的生物活性,旨在为其规模化制备和应用提供依据。

关键词: 迷迭香酸, 提取, 纯化, 生物活性

Abstract: Rosmarinic acid as a very strong antioxidants exists in rosemary with a high content. It has various biological activities such as anti-biotic, anti-inflammatory, anti-virus and anti-cancer activities. In order to offer more information for large-scale preparation and application, a brief review is presented on the extraction, purification methods. The biological activities of rosmarinic acid,such as antibiosis, antivirus, anti-oxidation, radical-scavenging, anti-inflammatory, immunoregulation, protecting nervous system, anti-radiation, antitumor, inhibition of xanthine oxidase and protection of livers and lungs are particularly discussed.

Key words: rosmarinic acid, extraction, purification, biological activity

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