电极修饰材料在分子印迹电化学传感器的应用研究进展

doi:10.3969/j.issn.0253-2417.2023.04.017

摘要/Abstract

摘要：

在简要介绍分子印迹聚合物(MIP)制备原理，以及分子印迹电化学传感器(MIECS)工作原理的基础上，综述了碳纳米材料、磁性材料和导电聚合材料3种电极修饰材料在MIECS中的应用。碳纳米材料主要涉及石墨烯及其系列衍生物、碳纳米管(CNT)；磁性材料在归纳对比了涂覆、磁吸附、电聚合这3种电极修饰方式之外，主要介绍了基于传统电极和基于磁控电极的磁性分子印记聚合物(MMIP)修饰；导电聚合材料的合成方法有化学合成、电化学聚合和微生物辅助聚合，重点叙述了电化学聚合法的特点。最后，对MIECS的发展前景和面临挑战进行了展望。

关键词: 分子印迹技术, 电化学传感器, 碳纳米材料, 磁性材料, 导电聚合物

Abstract:

Based on briefly introducing the preparation principle of molecularly imprinted polymer(MIP) and the working principle of molecularly imprinted electrochemical sensor(MIECS), the application of three kinds of electrode modification materials: carbon nanomaterials, magnetic materials, and conductive polymer materials in MIECS is reviewed. Carbon nanomaterials mainly involve graphene and its series derivatives, carbon nanotubes(CNT); magnetic materials In addition to the induction and comparison of the three electrode modification methods of coating, magnetic adsorption, and electropolymerization, it mainly introduces the methods based on traditional electrodes and Magnetic Molecularly Imprinted Polymer(MMIP) modification based on magnetron electrodes; the synthetic methods of conductive polymer materials include chemical synthesis, electrochemical polymerization and microorganism-assisted polymerization. The characteristics of electrochemical polymerization are described emphatically. Finally, the development prospects and challenges of MIECS are highlighted.

Key words: molecular imprinting technique, electrochemical sensor, carbon nanomaterials, magnetic materials, conductive polymer

中图分类号:

TQ35
O641

马春慧, 秦旭阳, 许慧娟, 李伟, 罗沙, 刘守新. 电极修饰材料在分子印迹电化学传感器的应用研究进展[J]. 林产化学与工业, 2023, 43(4): 127-139.

Chunhui MA, Xuyang QIN, Huijuan XU, Wei LI, Sha LUO, Shouxin LIU. Electrode Modification Materials for Molecularly Imprinted Electrochemical Sensors[J]. Chemistry and Industry of Forest Products, 2023, 43(4): 127-139.

图/表 3

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电极及修饰材料 electrode and modification material	修饰方式 modification method	分析物 analyte	分析方法 analytical method	检出限/ (mol·L^-1) detection limit	文献 ref.
MIP/MPS/Fe₃O₄@SiO₂/GCE	磁吸附 magnetic adsorption	敌草隆diuron	DPV	1.3×10^-8	[68]
MIP/MGO/Au/AuE	滴涂drop coating	氯霉chloramphenicol	CV	8.0×10^-10	[69]
MIP/Fe₃O₄@SiO₂/MPS/GCE	磁吸附magnetic adsorption	甲基对硫磷 methyl parathion	CV	1.22×10^-6*	[70]
MIP/Fe₃O₄/CPE	滴涂drop coating	四溴双酚A tetrabromobisphenol A	DPV	0.77×10^-9	[71]
MIP/MOFs/Fe₃O₄@PDA	磁吸附magnetic adsorption	土霉oxytetracycline	DPV	4.1×10^-10*	[72]
MIP/MWCNT/CS/Fe₃O₄@Au/AuE	涂覆/电聚合 coating/electropolymerization	链霉素streptomycin	DPV	1.5×10^-9	[73]
MIP/MWCNTs/Fe₃O₄/PMMA/CS/GCE	滴涂drop coating	卡那霉素kanamycin	DPV/CV	2.3×10^-11	[74]
MIP/Fe₃O₄@SiO₂/MGCE	滴涂drop coating	甲硝唑metronidazole	DPV	1.6×10^-8	[75]
CuFe₂O₄/MIPs/GCE	滴涂drop coating	溶菌酶lysozyme	DPV	1.5×10^-9*	[76]
Fe₃O₄@MIP/rGO/GCE	滴涂drop coating	木犀草素luteolin	DPV/CV	1×10^-12	[77]
MIP/Fe₃O₄@Au-GSH/MGCE	磁吸附magnetic adsorption	雌二醇estradiol	DPV	2.76×10^-9	[78]
Fe₃O₄@ZIF-8@MIP/AuE	磁吸附magnetic adsorption	肌氨酸sarcosine	CV	0.4×10^-12	[79]
MIP/Fe₃O₄@rGO/GCE	磁吸附magnetic adsorption	苋菜amaranth	DPV		[80]
MIP/Fe₃O₄@PANI/MGCE	磁吸附magnetic adsorption	肌酐creatinine	CV/DPV	0.35×10^-9	[81]
MIP/Fe₃O₄@PANI/rGO	磁吸附magnetic adsorption	谷胱甘肽glutathione	DPV	3×10^-9	[82]

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