马尾松树皮提取物抗脑缺血和抗脑肿瘤作用的研究

›› 2007, Vol. 27 ›› Issue (S1): 21-23.

• 研究报告 • Previous Articles Next Articles

Protective Effects of Masson's Pine Bark Extract on Incomplete Cerebral Ischemia of Mice and Brain Tumor of Nude Mice

ZHENG Guang-yao¹, WANG Cheng-zhang¹, XIE Heng², LI Ruo-da², CHEN Wen-ying¹, CHEN Hong-xia¹

1. Institute of Chemical Industry of Forest Products, CAF;Key and Open Lab. on Forest Chemical Engineering, SFA, Nanjing 210042, China;2. Institute of Songzhen Nutritional Resource, Lechang 512229, China

Received:2007-06-20 Revised:1900-01-01 Online:2007-10-20 Published:2007-10-20

Abstract

Abstract: To investigate the protective effects of masson's pine bark extract (MPBE) on incomplete cerebral ischemia of mice and brain tumor of nude mice,the model of acute incomplete cerebral ischemia in mice was established by ligating bilateral carotid arteries, and the model of intrabrain transplanted tumor in nude mice was established by implanting human brain tumor (SF763). The survival time was observed in these two models, respectively. Results showed: the survival time of mice by bilateral carotid arteries ligation was obviously prolonged with the dose of MPBE. The rate of life prolongation of nude mice by human brain tumor implantion was obviously increased with the dose of MPBE combining with ADM. MPBE may be useful for prevention of cerebral ischemia and brain tumor.

Key words: masson's pine bark extract, cerebral ischemia, brain tumor

CLC Number:

TQ91

ZHENG Guang-yao;WANG Cheng-zhang;XIE Heng;LI Ruo-da;CHEN Wen-ying;CHEN Hong-xia. Protective Effects of Masson's Pine Bark Extract on Incomplete Cerebral Ischemia of Mice and Brain Tumor of Nude Mice[J]. , 2007, 27(S1): 21-23.

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Protective Effects of Masson's Pine Bark Extract on Incomplete Cerebral Ischemia of Mice and Brain Tumor of Nude Mice

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