Chemistry and Industry of Forest Products ›› 2022, Vol. 42 ›› Issue (5): 45-55.doi: 10.3969/j.issn.0253-2417.2022.05.007
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Renxuan ZOU, Wengui DUAN(), Guishan LIN, Baoyu LI, Yucheng CUI
Received:
2021-12-17
Online:
2022-10-28
Published:
2022-11-02
Contact:
Wengui DUAN
E-mail:wgduan@gxu.edu.cn
About author:
段文贵,教授,博士生导师,主要从事生物质资源化学和有机合成研究; E-mail: wgduan@gxu.edu.cnCLC Number:
Renxuan ZOU, Wengui DUAN, Guishan LIN, Baoyu LI, Yucheng CUI. Synthesis, Antifungal Activity and 3D-QSAR Study of Novel 1, 3, 4-Thiadiazole-Thiourea Compounds Containing gem-Dimethylcyclopropane Ring[J]. Chemistry and Industry of Forest Products, 2022, 42(5): 45-55.
"
compounds1) | inhibition rate against the tested fungi/% | |||||||
F. oxysporum f. sp. cucumerinum | C. arachidicola | P. piricola | A. solani | G. zeae | R. solani | B. myadis | C. orbicalare | |
8a | 43.5 | 27.6 | 71.8 | 40.6 | 11.1 | 6.0 | 5.0 | 10.9 |
8b | 12.5 | 30.8 | 15.4 | 21.4 | 19.4 | 26.8 | 14.3 | 13.6 |
8c | 37.0 | 20.7 | 71.8 | 31.3 | 38.9 | 8.4 | 2.5 | 10.9 |
8d | 41.3 | 10.3 | 5.1 | 21.9 | 33.3 | 10.8 | 5.0 | 8.7 |
8e | 39.1 | 24.1 | 12.8 | 37.5 | 27.8 | 14.5 | 0 | 10.9 |
8f | 47.8 | 10.3 | 20.5 | 21.9 | 38.9 | 2.4 | 7.5 | 8.7 |
8g | 54.3 | 31.0 | 59.0 | 34.4 | 22.2 | 8.4 | 0 | 6.5 |
8h | 26.1 | 41.4 | 10.3 | 43.8 | 0 | 8.4 | 20.0 | 19.6 |
8i | 8.3 | 7.7 | 7.7 | 21.4 | 6.5 | 26.8 | 9.5 | 2.3 |
8j | 12.5 | 30.8 | 15.4 | 21.4 | 6.5 | 35.7 | 9.5 | 4.5 |
8k | 20.8 | 38.5 | 11.5 | 21.4 | 29.0 | 26.8 | 14.3 | 13.6 |
8l | 43.5 | 6.9 | 79.5 | 25.0 | 38.9 | 4.8 | 5.0 | 6.5 |
8m | 12.5 | 53.8 | 34.6 | 28.6 | 32.3 | 30.4 | 19.0 | 22.7 |
8n | 43.5 | 27.6 | 51.3 | 34.4 | 33.3 | 2.4 | 12.5 | 8.7 |
8o | 8.3 | 23.1 | 26.9 | 21.4 | 9.7 | 30.4 | 19.0 | 13.6 |
8p | 20.8 | 23.1 | 26.9 | 14.3 | 16.1 | 17.9 | 9.5 | 4.5 |
8q | 52.2 | 3.4 | 30.8 | 25.0 | 33.3 | 6.0 | 2.5 | 10.9 |
8r | 12.5 | 53.8 | 19.2 | 35.7 | 19.4 | 58.9 | 14.3 | 13.6 |
8s | 8.3 | 7.7 | 15.4 | 21.4 | 9.7 | 26.8 | 9.5 | 2.3 |
8t | 22.5 | 48.5 | 40.8 | 31.4 | 16.5 | 27.9 | 24.3 | 23.6 |
chlorothalonil* | 100 | 73.3 | 75.0 | 73.9 | 73.1 | 96.1 | 90.4 | 91.3 |
"
compounds1) | experimental value | predictive value | residue |
8a | -2.151 | -2.228 | 0.077 |
8b | -3.528 | -3.504 | -0.024 |
8c | -2.167 | -2.093 | -0.074 |
8d | -3.843 | -3.744 | -0.099 |
8e | -3.425 | -3.416 | -0.008 |
8f | -3.18 | -3.203 | 0.023 |
8g | -2.42 | -2.33 | -0.090 |
8j | -3.336 | -3.353 | 0.018 |
8k | -3.528 | -3.560 | 0.033 |
8l | -2.053 | -2.096 | 0.043 |
8m | -2.884 | -2.877 | -0.007 |
8n | -2.585 | -2.603 | 0.018 |
8o | -3.042 | -3.046 | 0.004 |
8q | -2.941 | -2.941 | 0.000 |
8r | -3.256 | -3.264 | 0.008 |
8s | -3.371 | -3.449 | 0.078 |
8h* | -3.518 | -3.541 | 0.023 |
8i* | -3.674 | -3.730 | 0.056 |
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