松针叶绿素-胡萝卜素软膏体外抗脂质过氧化作用的研究

doi:10.3969/j.issn.0253-2417.2013.01.008

›› 2013, Vol. 33 ›› Issue (1): 45-48.doi: 10.3969/j.issn.0253-2417.2013.01.008

• 1研究报告 • Previous Articles Next Articles

Anti-lipid Peroxidation of Chlorophyll-carotene Paste from Pine Needles in Vitro

ZHENG Guang-yao¹, HE Ling², BO Cai-ying¹, XIE Heng³, LIU Dong-qin², LI Ruo-da³

1. Institute of Chemical Industry of Forest Products, CAF;National Engineering Lab. for Biomass Chemical Utilization;Key and Open Lab. of Forest Chemical Engineering, SFA, Nanjing 210042, China;2. Department of Pharmacology, China Pharmaceutical University, Nanjing 210009, China;3. Zhongjianxing Group Corporation Limited, Lechang 512229, China

Received:2012-06-28 Revised:1900-01-01 Online:2013-02-28 Published:2013-02-28

Abstract

Abstract: Anti-lipid peroxidation of chlorophyll-carotene paste from pine needles was investigated in vitro. MDA production in rat liver homogenate and mitochondria spontaneously formed or induced by V_C-Fe²⁺ system were measured. The results showed that the chlorophyll-carotene paste could inhibit the generation of MDA in liver homogenate under spontaneous and induced conditions, as well as in liver mitochondria under induced condition, with IC₅₀ of 398.72 mg/L, 355.05 mg/L and 687.02 mg/L, respectively. The swelling of liver mitochondria was also inhibited with dose-response relationship. It is suggested that chlorophyll-carotene paste from pine needles possessed anti-oxidant activity in vitro.

Key words: pine needles, extract, liver homogenate, mitochondria, lipid peroxidation

CLC Number:

TQ35
R961

ZHENG Guang-yao;HE Ling;BO Cai-ying;XIE Heng;LIU Dong-qin;LI Ruo-da. Anti-lipid Peroxidation of Chlorophyll-carotene Paste from Pine Needles in Vitro[J]. , 2013, 33(1): 45-48.

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Anti-lipid Peroxidation of Chlorophyll-carotene Paste from Pine Needles in Vitro

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