左旋海松酸单离与应用研究进展

doi:10.3969/j.issn.0253-2417.2016.03.019

摘要/Abstract

摘要： 概述了左旋海松酸的单离工艺及化学性质,综述了近几年来左旋海松酸及其衍生物的研究进展。左旋海松酸的单离提纯主要采用胺化、重结晶及毛细管柱分离等方法。根据左旋海松酸的结构特点,通过对其单离纯品进行羧基酯化、双烯加成等,可合成一系列用途广泛的精细化学品,如耐热导电材料、表面活性剂等,也可以被作为一种很好的手性原料用于选择性合成具有生物活性的化合物。

关键词: 左旋海松酸, 单离, 精细化学品, 生物活性

Abstract: This article outline the isolation process, chemical properties and recent progress of levopimaric acid and its derivatives in recent years. The isolation of levopimaric acid mainly depended on the amine reaction, recrystallization and capillary column separation methods. According to the structural characteristics, the pure sample of levopimaric acid could be used to synthesize a wide range of fine chemicals, such as heat conductive material, surface active agent by carboxyl esterification and diene addition, etc. It could be used as a good compound for the selective synthesis of chiral materials with biological activity, too.

Key words: levopimaric acid, isolation, fine chemicals, biological activity

中图分类号:

TQ35

齐志文, 蒋丽红, 王亚明, 张塞. 左旋海松酸单离与应用研究进展[J]. 林产化学与工业, 2016, 36(3): 127-132.

QI Zhi-wen, JIANG Li-hong, WANG Ya-ming, ZHANG Sai. Research Advance in Isolation and Application of Levopimaric Acid[J]. Chemistry and Industry of Forest Products, 2016, 36(3): 127-132.

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