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›› 2008, Vol. 28 ›› Issue (04): 44-48.

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Studies on Chemical Constituents and Antifungal Activity of Turkish Galls

LIU Yan-lin1, DENG Xu-ming1, WANG Da-cheng1, LEI Lian-cheng1, HAN Wen-yu1, ZHAO Rui-li1, WANG Jiao-yu2   

  1. 1. College of Animal and Veterinary Medicine, Jilin University, Changchun 130062, China;2. Fishery Technical Extension Center of Jilin Province, Changchun 130012, China
  • Received:2007-10-10 Revised:1900-01-01 Online:2008-08-30 Published:2008-08-30

Abstract: Chemical constituents of Turkish galls and their antifungal activities were studied. The constituents were isolated and purified by silica gel, Sephadex LH-20 column chromatography and preparative thin-layer chromatography,and their structures were elucidated by various spectroscopic methods.The method of minimal inhibitory concentration(MIC) was used to evaluate the antifungal activity of the extracts and compounds from Turkish galls. Seven compounds were isolated and their structures were identified as gallic acid (Ⅰ), m-digallic acid(Ⅱ), p-digalloyl acid(Ⅲ), methyl gallate(Ⅳ), ethyl gallate(Ⅴ), 1,2,3,6-tetra-O-galloyl-β-D-glucose(Ⅵ), and 1,2,3,4,6-penta-O-galloyl-β-D-glucose(Ⅶ). The EtOAc extractive exhibits the strongest bacteriostatic activity. Compounds Ⅲ and Ⅴ are isolated from this gall for the first time.

Key words: fagaceae, Turkish galls, antifungal activity

CLC Number: